What are the early signs of shingles?

  • The first sign that you may have shingles is a painful, burning or tingling sensation that will appear in one area on a single side of the body. This tingling sensation can appear days before the shingles rash even starts to develop. It is difficult to identify shingles in this early stage because without the presence of a rash the pain may appear to not be associated with a particular disease.
  • Next, a painful rash with blisters will develop in the same area as the previous painful/burning/tingling sensation, most commonly, in a single stripe around either the left or right side of the body. The rash will start out as one or two blisters and will spread over the next few days. This is often when most people recognize they may have shingles.
  • You may also experience fever, headache, and upset stomach when the rash starts to form.

Importantly, for shingles treatment to be most effective, it must be started within 5 days of the onset of symptoms.

There are an estimated one million cases of shingles each year in the U.S. Almost one out of every three people in the U.S. will develop shingles in their lifetime.

About The Valnivudine™ (Formerly FV-100) Clinical Trial

A new clinical trial is seeking participants to test an investigational drug that is designed for the pain associated with shingles, known as post-herpetic neuralgia or PHN. PHN can last for several months or even years after the shingles rash goes away.

If you are 30 years of age or older, have shingles, and qualify for the study, you will receive the following at no cost:

  • Study medication for shingles
  • Study-related care from a local doctor

Health insurance and referrals are not required to participate.

Contact a Testing Center

The Valnivudine™ study is now enrolling. Please contact a testing center near you to find out more information on whether you are eligible to participate in the Clinical Trial.

Find Out if You May be Eligible to Participate in the Valnivudine™ Clinical Trial

Visiting a doctor promptly within 5 days of the first blister can help ensure you get the advice necessary to overcome the illness.

Dr. Stephen K. Tyring, M.D., Ph.D., Dermatologist and Virologist